Prof. Okun’s research focuses on basic and translational Neuroimmunology. Prof. Okun’s laboratory studies how B-cells, a type of immune cells that produce antibodies, are involved in cognitive decline in Down syndrome and Alzheimer disease. The laboratory also develops DNA vaccination strategies to delay the progression Alzheimer’s disease-related symptoms in Down syndrome (DS). In addition, the laboratory explores the mechanisms of fetal-maternal transfer involved in maternal cognitive decline.
